OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Sickle Cell Anemia is caused by a “point” mutation. Which of the following correctly describes this type of mutation?
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A nucleotide or group of nucleotides is inserted into the wrong location in the DNA. This changes the order in which the nucleotides are “read” and results in the synthesis of an incorrect amino acid sequence.
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A nucleotide or group of nucleotides is deleted from the DNA. This changes the order in which the nucleotides are “read” and results in the synthesis of an incorrect amino acid sequence.
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An incorrect nucleotide is substituted for the correct nucleotide. This changes one codon in the gene sequence. This results in a change in one amino acid in the protein. This change in one amino acid changes the overall shape/function of the protein.
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Several incorrect nucleotides are substituted for their correct counterparts. This changes several of the amino acids in the protein and results in a protein that is misshapen and not functional.
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Explanation:
Detailed explanation-1: -Sickle-cell anemia results from an A leads to T transversion in the second nucleotide of codon 6 of the beta-globin gene.
Detailed explanation-2: -Base substitutions are the simplest type of gene-level mutation, and they involve the swapping of one nucleotide for another during DNA replication.
There is 1 question to complete.