LIFE SCIENCE

Detailed explanation-1: -This theory states that all reaction molecules are in constant motion, and for a chemical reaction to occur they have to collide in order to form a product. A collision only leads to successful product formation if the molecules collide with sufficient energy, as well as in the correct orientation.

Detailed explanation-2: -Electrostatic interaction: In an aqueous environment, the oppositely charged groups in amino acid side chains within the active site and substrates attract each other, which is termed electrostatic interaction.

Detailed explanation-3: -The simplest model of enzyme-substrate interaction is the lock-and-key model, in which the substrate fits precisely into the active site (Figure 2.24). In many cases, however, the configurations of both the enzyme and substrate are modified by substrate binding-a process called induced fit.