OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The DNA Replication occur in the following direction
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3’ to 5’
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5’ to 3’
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3’ to 3’
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5’ to 5’
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Explanation:
Detailed explanation-1: -DNA polymerases can only make DNA in the 5’ to 3’ direction, and this poses a problem during replication. A DNA double helix is always anti-parallel; in other words, one strand runs in the 5’ to 3’ direction, while the other runs in the 3’ to 5’ direction.
Detailed explanation-2: -DNA replication occurs in a 5’ to 3’ direction because the enzyme DNA polymerase has the ability to incorporate nucleotide only at the 3’ end of a DNA strand. This happens because DNA polymerase requires the hydroxyl group present at the 3’ end to catalyze the phosphodiester bond formation.
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