LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The induced fit model is preferred over the lock-and-key model because
A
some enzymes catalyze multiple reactions.
B
all substrates have the same shape.
C
the active site is a polar region.
D
the enzyme and substrate match each other structurally and chemically.
Explanation: 

Detailed explanation-1: -The induced fit mechanism is the most widely accepted because it is a development of the lock and key mechanism in that it suggests that the enzyme’s active site changes slightly in order for the substrate to fit, whereas the lock and key mechanism does not suggest that the active site changes at all.

Detailed explanation-2: -In addition, the induced fit model is better able to explain how catalysis actually occurs. A conformational change, which would place stress on the bonds within the substrate can explain how bonds would break in order for the products to form. This makes the induced fit model the more widely accepted model of the two.

Detailed explanation-3: -The lock and key model states that the active site of an enzyme precisely fits a specific substrate. The induced fit model states that the active site of an enzyme will undergo a conformational change when binding a substrate, to improve the fit.

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