LIFE SCIENCE

Detailed explanation-1: -When an enzyme is denatured, it loses it native conformation, or three-dimensional structure. A denatured enzyme is unable to bind to its substrate and increase the chemical rate of reaction.

Detailed explanation-2: -Enzyme denaturation happens when the structure of a protein and its functional group undergo conformational changes, resulting in inactivity. Denatured proteins have a looser, more random structure, and the majority of them are insoluble.

Detailed explanation-3: -Denaturation implies the destruction of the tertiary structure of a protein molecule and the formation of random polypeptide chains.

Detailed explanation-4: -Denaturation is a process in which proteins lose their shape and, therefore, their function because of changes in pH or temperature.