OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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High temperature
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Low pH
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High pH
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Low temperature
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Detailed explanation-1: -Secondary, tertiary and quaternary protein structure is easily changed by a process called denaturation. These changes can be quite damaging. Heating, exposure to acids or bases and even violent physical action can cause denaturation to occur.
Detailed explanation-2: -Acids and bases can significantly change the environmental pH of proteins, which disrupts the salt bridges and hydrogen bonding formed between the side chains, leading to denaturation.
Detailed explanation-3: -pH denaturation. At extreme pH, the main force unfolding the protein is the repulsion between charged groups on the protein molecule. CpGAL exhibits structural and functional stability over a wide range of pH.
Detailed explanation-4: -Changing the pH disrupts the hydrogen bonds, and this changes the shape of the protein.