LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What happens to an mRNA when the protein it is used to make is no longer needed?
A
it is broken down into amino acids and they are reused
B
it is broken down into nucleotides and they are reused
C
it is broken down into glucose and reused
D
it goes back to the nucleus
Explanation: 

Detailed explanation-1: -mRNA formed in the nucleus is transported out of the nucleus and into the cytoplasm where it attaches to the ribosomes. Proteins are assembled on the ribosomes using the mRNA nucleotide sequence as a guide. Thus mRNA carries a “message” from the nucleus to the cytoplasm.

Detailed explanation-2: -As highlighted earlier, damage to mRNA, depending on its type, is highly detrimental to its decoding capacity, and unless dealt with, it could lead to the production of toxic protein products. Even more detrimental is the ability of damaged mRNA to drastically affect ribosome homeostasis through stalling.

Detailed explanation-3: -The pre-mRNA has to go through some modifications to become a mature mRNA molecule that can leave the nucleus and be translated. These include splicing, capping, and addition of a poly-A tail, all of which can potentially be regulated – sped up, slowed down, or altered to result in a different product.

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