OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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it separates tRNA in the A site from the growing polypeptide
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it binds to the stop codon in the A site in place of a tRNA
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it releases the amino acid from its tRNA to allow the amino acid to form a polypeptide
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it releases the ribosome from the ER to allow polypeptides into the cytosol
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Detailed explanation-1: -It binds to the stop codon in the A site in place of a tRNA. It releases the amino acid from its tRNA to allow the amino acid to be added to the growing polypeptide. It supplies a source of energy for termination of translation and the release of the polypeptide.
Detailed explanation-2: -Translation termination involves two classes of release factors (RFs). Class 1 RFs recognize stop codons within the ribosomal A site and trigger the hydrolysis of the ester bond connecting the peptide chain and the tRNA at the ribosomal P site.
Detailed explanation-3: -During translation termination, release factor protein catalyzes a hydrolytic reaction in the large subunit peptidyl transferase center to release the finished polypeptide chain.