OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ribosome
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mitochondria
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nucleus
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golgi bodies
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Detailed explanation-1: -The small ribosomal subunit mediates the interactions between mRNA codons and tRNA anticodons that determine the order in which amino acids are assembled into protein. The large ribosomal subunit contains the peptidyl transferase center, the site where peptide bond formation occurs.
Detailed explanation-2: -The formation of each peptide bond is catalyzed by peptidyl transferase, an RNA-based enzyme that is integrated into the 50S ribosomal subunit. The energy for each peptide bond formation is derived from the high-energy bond linking each amino acid to its tRNA.
Detailed explanation-3: -The ribosome catalyzes the peptide bond formation by the nucleophilic attack of an aminoacyl-tRNA in the A-site on ester carbon of the peptidyl-tRNA in the P-site.