OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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DNA polymerase
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peptidyl transferase
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Aminoacyl-tRNA synthetases
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RNA polymerase
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Detailed explanation-1: -Peptidyl transferase is an enzyme that catalyzes the addition of an amino acid residue in order to grow the polypeptide chain in protein synthesis. It is located in the large ribosomal subunit, where it catalyzes the peptide bond formation. It is composed entirely of RNA.
Detailed explanation-2: -An enzyme involved in the process of translation is peptidyl transferase. What is the role of peptidyl transferase? (A) To catalyze the formation of phosphodiester bonds between nucleotides in mRNA. (B) To transfer tRNA molecules to the mRNA strand to form a polypeptide chain.
Detailed explanation-3: -The peptidyl transferase activity of the ribosome catalyzes peptide bond formation between the adjacent amino acids. Once fMet is bound to the second amino acid, it no longer binds to its tRNA. The ribosome translocates (facilitated by elongation factors) towards the 3′ end of the mRNA by one codon.