LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following enzyme can protect the degradation of DNA strands by nucleases?
A
Helicase enzyme
B
Single strand binding proteins
C
Topoisomerase I
D
Topoisomerase II
Explanation: 

Detailed explanation-1: -The first nucleotide polymerizing enzyme, DNA polymerase, was discovered in 1957. The free nucleotides that serve as substrates for this enzyme were found to be deoxyribonucleoside triphosphates, and their polymerization into DNA required a single-stranded DNA template.

Detailed explanation-2: -The enzyme that digests DNA in macrophage lysosomes is deoxyribonuclease II (DNase II), also called DNase II or acid DNase, which has the optimal pH at acid condition (Evans and Aguilera 2003).

There is 1 question to complete.