LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
which of the following enzyme catalyze the removal of RNA primer
A
DNA Polymerase II
B
DNA Polymerase I
C
DNA Polymerase IIi
D
DNA Polymerase II and DNA Polymerase III
Explanation: 

Detailed explanation-1: -In E. coli, RNA primers are removed by the combined action of RNase H, an enzyme that degrades the RNA strand of RNA-DNA hybrids, and polymerase I.

Detailed explanation-2: -Primase is an enzyme that synthesizes short RNA sequences called primers. These primers serve as a starting point for DNA synthesis. Since primase produces RNA molecules, the enzyme is a type of RNA polymerase.

Detailed explanation-3: -DNA Polymerase I possesses a 3´→5´ exonuclease activity or “proofreading” function, which lowers the error rate during DNA replication, and also contains a 5´→3´ exonuclease activity, which enables the enzyme to replace nucleotides in the growing strand of DNA by nick translation.

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