OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is false about purine and pyrimidine bases?
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They are hydrophobic and relatively insoluble in water at the near-neutral pH of the cell
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At acidic or alkaline pH the bases become charged and their solubility in water increases
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Purines have two rings in their structure, but pyrimidine bases have only one ring
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At acidic or alkaline pH the bases become charged and their solubility in water decreases
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Explanation:
Detailed explanation-1: -Conclusion: In summary, the false statement about purine and pyrimidine bases is that at acidic or alkaline pH, the bases become charged and their solubility in water decreases. In reality, their solubility increases at acidic or alkaline pH due to the charged nature of the bases.
Detailed explanation-2: -Answer and Explanation: The statement “in DNA, a pyrimidine always pairs with a purine” is true.
Detailed explanation-3: -Purines always bond with pyrimidines by forming hydrogen bonds. The two bases, adenine (A) and guanine (G) are purines while cytosine (C), thymine (T) and uracil (U) are pyrimidines. Adenine always bonds with thymine by two hydrogen bonds (A=T) in a DNA molecule.
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