LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following mutations would be MOST likely to have a harmful effect on an organism?
A
a deletion of three nucleotides near the middle of a gene.
B
a single nucleotide deletion in the middle of an intron.
C
a single nucleotide deletion near the end of a coding sequence.
D
a single nucleotide insertion downstream of, and close to, the start of the coding sequence.
Explanation: 

Detailed explanation-1: -So, the correct option is ‘A single base insertion near the start of the coding sequence’.

Detailed explanation-2: -Answer and Explanation: (e) Insertion of one nucleotide is most likely to drastically affect a protein’s sequence. Insertion/deletion of any number of nucleotide/s (except in the multiple of three) will result in the mutation refer to as a frame-shift mutation.

There is 1 question to complete.