LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

MOLECULAR BIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why are insertion and deletion (frameshift) mutations so harmful?
A
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
B
They insert things that an organism doesn’t need.
C
They often delete things that organisms need.
D
Insertion and deletions are not any more harmful than substitution mutations.
Explanation: 

Detailed explanation-1: -Because an insertion or deletion results in a frame-shift that changes the reading of subsequent codons and, therefore, alters the entire amino acid sequence that follows the mutation, insertions and deletions are usually more harmful than a substitution in which only a single amino acid is altered.

Detailed explanation-2: -In a chromosome deletion, the frame shift mutation will not occur if the number of bases is three. Because the bases are always read as triplet codons which has a set of three bases.

Detailed explanation-3: -Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.

There is 1 question to complete.