OBJECTIVE LIFE SCIENCE
MOLECULAR BIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Why are insertion and deletion mutations so harmful?
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They change all of the codons from the mutation on down the line, which changes the amino acid sequence
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They insert things that an organism doesn’t need.
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They often delete things that organisms need.
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Insertion and deletions are not any more harmful than substitution mutations.
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Explanation:
Detailed explanation-1: -Insertion or deletion of one or more nucleotides during replication can also lead to another type of mutation known as a frameshift mutation. The outcome of a frameshift mutation is complete alteration of the amino acid sequence of a protein.
Detailed explanation-2: -A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons.
Detailed explanation-3: -An insertion or deletion involving a number of base pairs that is not a multiple of three, which consequently disrupts the triplet reading frame of a DNA sequence.
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