OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Lyn
|
|
|
JAK-STAT
|
|
|
MAPK
|
|
|
None of the above
|
Detailed explanation-1: -An immunoreceptor tyrosine-based inhibitory motif (ITIM), is a conserved sequence of amino acids that is found intracellularly in the cytoplasmic domains of many inhibitory receptors of the non-catalytic tyrosine-phosphorylated receptor family found on immune cells.
Detailed explanation-2: -Fc receptor IIB for IgG (FcRIIB) regulates phagocytosis of parasites and parasitized erythrocytes, antigen presentation to T cells and the production of malarial antibodies by B cells. Macrophages are important in the immune response to malaria, both as antigen-presenting cells (APCs) and phagocytes.
Detailed explanation-3: -Fc receptors are found on a number of cells in the immune system including phagocytes like macrophages and monocytes, granulocytes like neutrophils and eosinophils, and lymphocytes of the innate immune system (natural killer cells) or adaptive immune system (e.g., B cells).