LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cytotoxic T-Cells enter circulation and search for antigen displaying cells, attack and destroy antigens indirectly by
A
secreting monokines
B
secreting lymphokines
C
secretion of perforin
D
secreting lymphokines
Explanation: 

Detailed explanation-1: -Cytotoxic cells are involved in the direct killing of intracellular pathogens, and the elimination of mutated and cancerous cells. These immune responses are generated by T cells when they recognize an antigen, which is presented to them by antigen-presenting cells.

Detailed explanation-2: -Another way cytotoxic T cells kill target cells is by releasing cytotoxic granules. These granules are sent in the direction of the target cell and contain two proteins that work in tandem to destroy cells from the inside out. The first protein, perforin, creates holes in the membrane of the target cell.

Detailed explanation-3: -T-Cell Immunity CTLs are able to kill target cells directly by inducing apoptosis. Nucleases and other enzymes activated in the apoptotic process may help destroy the viral genome, thus preventing the assembly of virions and potential infection of other cells.

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