OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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How long does Immunoglobulin G circulate in serum providing protection?
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Months to Years
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Weeks to Months
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Less than 72 hours
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5-10 Days
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Explanation:
Detailed explanation-1: -In humans, the average half-life of IgG in circulation is approximately 3 weeks2 and in mice it is 6–8 days3. However, in FcRn−/−mice the half-life of IgG in circulation is reduced to 1 day4 and the mice cannot maintain IgG homeostasis, resulting in a 70–80% reduction of the total level of IgG.
Detailed explanation-2: -IgG could be detected as early as 4 days after the onset of illness.
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