OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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In order to activate the helper T cells, antigens need to be presented by which type of MHC receptors?
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MHC I
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MHC II
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Because dendritic cells express both class I and class II MHC proteins, they can activate both cytotoxic and helper T cells.
Detailed explanation-2: -The main function of major histocompatibility complex (MHC) class II molecules is to present processed antigens, which are derived primarily from exogenous sources, to CD4(+) T-lymphocytes. MHC class II molecules thereby are critical for the initiation of the antigen-specific immune response.
Detailed explanation-3: -Dendritic cells (DCs) Dendritic cells have the broadest range of antigen presentation and are necessary for activation of naive T cells. DCs present antigen to both helper and cytotoxic T cells.
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