LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
In order to activate the helper T cells, antigens need to be presented by which type of MHC receptors?
A
MHC I
B
MHC II
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Because dendritic cells express both class I and class II MHC proteins, they can activate both cytotoxic and helper T cells.

Detailed explanation-2: -The main function of major histocompatibility complex (MHC) class II molecules is to present processed antigens, which are derived primarily from exogenous sources, to CD4(+) T-lymphocytes. MHC class II molecules thereby are critical for the initiation of the antigen-specific immune response.

Detailed explanation-3: -Dendritic cells (DCs) Dendritic cells have the broadest range of antigen presentation and are necessary for activation of naive T cells. DCs present antigen to both helper and cytotoxic T cells.

There is 1 question to complete.