LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Lymph nodes and spleen have germinal centers in which B cells respond to antigen and produce antibodies. A function unique to the spleen w.r.t. other peripheral lymphoid organs is
A
filtration of blood-borne pathogens.
B
production of dendritic cells.
C
production of red blood cells.
D
antigen presentation
Explanation: 

Detailed explanation-1: -The lymph nodes and other lymphatic structures like the spleen and thymus hold special white blood cells called lymphocytes. These can rapidly multiply and release antibodies in response to bacteria, viruses, and a range of other stimuli from dead or dying cells and abnormally behaving cells such as cancer cells.

Detailed explanation-2: -The spleen is a key lymphoid organ for generating B-lymphocyte (B cell)-mediated humoral immunity. This review examines the key features and functions of splenic B cells. Splenic B cell subsets, including virgin, memory, and CD5+ B cells, are characterized by their phenotypic markers and functions.

Detailed explanation-3: -The germinal center (GC) is a specialized microstructure that forms in secondary lymphoid tissues, producing long-lived antibody secreting plasma cells and memory B cells, which can provide protection against reinfection.

There is 1 question to complete.