OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Lyn-mediated phosphorylation of ITAMs triggers which 2 pathways, leading to allergic effects?
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JAK-STAT
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PKC
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MAPK
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None of the above
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Explanation:
Detailed explanation-1: -So, the correct answer is ‘IgG and mast cells’.
Detailed explanation-2: -Allergic responses have two phases: the acute and the chronic, observed as Wheal and Flare. This generally occurs rapidly after allergen exposure (<1hour). It is caused by the degranulation of mast cells and the release of histamine and other mediators.
There is 1 question to complete.