LIFE SCIENCE

Detailed explanation-1: -Since, mast cells generate and release multi-potent molecules, such as histamine, proteases, prostanoids, leukotrienes, heparin, and many cytokines, chemokines, and growth factors, they have the capacity to be involved in regulating the functions of many organs and tissues.

Detailed explanation-2: -Chemokines are small proteins (8-12 kD polypeptides) secreted by the cells of innate and adaptive immunity that mediate many of the functions of these cells, including recruitment of other cells. They are classified into families: CC, CXC and CX3C.

Detailed explanation-3: -Additionally, basophils secrete an expansive array of other inflammatory mediators including cytokines and chemokines that further sustain and orchestrate heterogeneous asthmatic responses24.