Place the sequence of the 1st exposure of humoral immunity in order. B-cells $rightarrow$ plasma cells $rightarrow$ produce immunoglobulins called antibodiesThe antigen-antibody complex inactivates the antigenHelper T-Cells when activated secrete lymphokines $rightarrow$ stimulates large clones of B-cells and some memory B-Cellsantibodies circulate in blood and lymph and can bind to bacteria, toxins, and free virusesclones of memory B-Cells remain in lymphoid tissue awaiting antigen and re-appearance.

SIGNALLING IMMUNOLOGY CANCER

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Place the sequence of the 1st exposure of humoral immunity in order. B-cells

A	3, 1, 4, 2, 5
B	1, 3, 5, 4, 2
C	2, 4, 5, 1, 3
D	3, 2, 5, 4, 1

Explanation:

Detailed explanation-1: -Interaction with antigens causes B cells to multiply into clones of immunoglobulin-secreting cells. Then the B cells are stimulated by various cytokines to develop into the antibody-producing cells called plasma cells.

Detailed explanation-2: -The first antibodies to be produced in a humoral immune response are always IgM, because IgM can be expressed without isotype switching (see Figs 4.20 and 9.8).

There is 1 question to complete.

LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER