OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The high-affinity IgE receptor FcRI linking receptors trigger ____ phosphorylation of ITAMs.
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oxidative
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Lyn-mediated
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glucose
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protein
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Explanation:
Detailed explanation-1: -The high-affinity IgE receptor, also known as FcRI, or Fc epsilon RI, is the high-affinity receptor for the Fc region of immunoglobulin E (IgE), an antibody isotype involved in the allergy disorder and parasites immunity. FcRI is a tetrameric receptor complex that binds Fc portion of the heavy chain of IgE.
Detailed explanation-2: -FcRI, the high-affinity IgE receptor, distinguishes Ag–IgE interactions and drives cellular allergic responses [9]. FcRI is a unique molecular target that initiates different functional outcomes of MC responses and allergic inflammation [10, 11].
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