LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The thymus is the location where ____ become immunocompetent
A
B-cells
B
antibodies
C
antigens
D
T-Cells
Explanation: 

Detailed explanation-1: -The thymus gland is the primary lymphoid organ for lymphocyte development. The red bone marrow produces B-lymphocytes (B cells) and T lymphocytes (T cells). B cells achieve immunocompetence (ability to recognize a specific antigen) in bone marrow. T cells migrate to the thymus gland, where they become immunocompetent.

Detailed explanation-2: -The thymus is divided into two main regions, a peripheral cortex and a central medulla (see Fig. 7.7). Most T-cell development takes place in the cortex; only mature single-positive thymocytes are seen in the medulla. At the outer edge of the cortex, in the subcapsular region of the thymus (Fig.

Detailed explanation-3: -The correct answer is (B) lymphocytes.

Detailed explanation-4: -In the thymus, T cells develop their specific T cell markers, including TCR, CD3, CD4 or CD8, and CD2. T cells also undergo thymic education through positive and negative selection. The thymus is a multi-lobed organ composed of cortical and medullary areas surrounded by a capsule.

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