OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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This protein increases the blood vessels permeability to WBCs and other substances involved in the immune response.
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histamine
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complement
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lysozyme
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defensin
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Explanation:
Detailed explanation-1: -Histamine is a major preformed mediator released by mast cells and it strongly increases vascular permeability.
Detailed explanation-2: -Mast cells release mediators that increase both leukocyte adhesion to the venular endothelium and vascular permeability during reperfusion (47).
Detailed explanation-3: -Mast cells release histamine as well as other vasoactive molecules, which cause urticaria (hives). If the antigen activates mast cells in deeper tissue, this can lead to angioedema.
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