OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Upon inhalation, a small dust particle reaches the alveolus. Which of the following innate immune mechanism gets activated?
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the released granular contents of your granulocytes.
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the physical barrier produced by hairs.
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phagocytosis by macrophages.
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mucus combined with the movement of cilia of the lining cells.
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Explanation:
Detailed explanation-1: -Macrophages work as innate immune cells through phagocytosis and sterilization of foreign substances such as bacteria, and play a central role in defending the host from infection. However, residual macrophages in intestinal mucosa can potentially reduce inflammation to a greater extent than those in other tissues.
Detailed explanation-2: -Innate immunity forms a protective line of defense in the early stages of pulmonary infection. The primary cellular players of the innate immunity against respiratory infections are alveolar macrophages (AMs), dendritic cells (DCs), neutrophils, natural killer (NK) cells, and innate lymphoid cells (ILCs).
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