LIFE SCIENCE

OBJECTIVE LIFE SCIENCE

SIGNALLING IMMUNOLOGY CANCER

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What do IL-4 and IL-13 stimulate?
A
TH2 responses to increase IgE production by B cells
B
TH1 responses to increase IgE production by B cells
C
TH2 responses to increase IgE production by T cells
D
TH1 responses to increase IgE production by T cells
Explanation: 

Detailed explanation-1: -Mast Cells Produce IL-4 and IL-13 Mast cell cytokine secretion plays a pivotal role in the pathogenesis of allergic disease and inflammation [16].

Detailed explanation-2: -Both IL-4 and IL-13 induce IgE switching and IgE synthesis by human B cells activated by CD4+ T cells, Epstein-Barr virus transformation, or CD40 stimulation.

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