OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
thymus
|
|
|
pancreas
|
|
|
bone marrow
|
|
|
thryoid
|
Detailed explanation-1: -T lymphocytes develop from a common lymphoid progenitor in the bone marrow that also gives rise to B lymphocytes, but those progeny destined to give rise to T cells leave the bone marrow and migrate to the thymus (see Fig. 7.2). This is the reason they are called thymus-dependent (T) lymphocytes or T cells.
Detailed explanation-2: -Bone marrow is major organ for the development and maturation of B cells. B cells are generated from HSCs and developed in bone marrow before they egress into peripheral blood to reach peripheral lymphoid organs. Specific cellular niches for B-cell development include CXCL12-expressing cells and IL-7-expressing cells.
Detailed explanation-3: -Both B and T cells originate in the bone marrow. These cells are involved in adaptive immunity. They are a type of lymphocytes.