OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IgM
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IgG
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IgA
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IgE
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Detailed explanation-1: -In contrast to IgG molecules that contain one Fc domain, pentameric IgM has five different Fc domains on the same molecule, facilitating rapid complement activation when a single IgM molecule recognizes a pathogen.
Detailed explanation-2: -Immunoglobulin A (IgA) is the most abundant type of antibody in the body, comprising most of the immunoglobulin in secretions and a significant amount of circulating immunoglobulin. In secretions, it serves to protect the mucosal tissues from microbial invasion and maintain immune homeostasis with the microbiota.
Detailed explanation-3: -Due to the affinity maturation and class switching processes, IgG and IgA antibodies typically have substantially higher affinities than IgM antibodies [18, 19].