OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which is not a characteristic of T1 Helper cells ____ Antigen-specific local inflammatory response?
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Amplifies Cytotoxic T-lymphocyte (CTL) response
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Promotes phagocytosis by macrophage and neutrophils
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Down-regulates the further development of TH2 cells
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Enhances role of mast cells, basophils, and eosinophils
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Explanation:
Detailed explanation-1: -Allergens (or antigens) are presented to T-cells by Antigen-presenting cells (APCs) during the sensitization phase of Type I hypersensitivity.
Detailed explanation-2: -TReg cells have a key role in promoting and maintaining tolerance to allergens by regulating both innate and adaptive allergen-triggered immune response. Allergic diseases are associated with a failure to develop tolerance towards a specific allergen leading to the emergence of a pathogenic Th2 immune response.
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