OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which T-Cell surface marker receives activation co-signal from CD80/86 molecule on APC?
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CD28
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LFA-1
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CD20
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CD26
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Explanation:
Detailed explanation-1: -The CD28 molecule, a disulfide-linked homodimer expressed on peripheral T cells and thymocytes, mediates an essential costimulatory signal following engagement of the T cell receptor (TCR).
Detailed explanation-2: -Thus, the presence of CD28 on the T cells allowed these cells to absorb both Ld and B7-1, presumably in the form of membrane vesicles containing these two molecules.
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