OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which type of epithelial cells produce innate cytokines that affect DCs and induce allergen-specific TH2 cells, which trigger B cell isotope switch to IgE?
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skin epithelial cells
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intestinal epithelial cells
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Interleukin (IL)-4 is a key cytokine in the development of allergic inflammation. It is associated with induction of the isotype switch and secretion of IgE by B lymphocytes [1].
Detailed explanation-2: -IgE is produced by plasma cells located in lymph nodes draining the site of antigen entry or locally, at the sites of allergic reactions, by plasma cells derived from germinal centers developing within the inflamed tissue.
There is 1 question to complete.