MCQ IN MEDICINE

Detailed explanation-1: -Pernicious anemia is a relatively rare autoimmune disorder that causes diminishment in dietary vitamin B12 (cobalamin) absorption, resulting in B12 deficiency and subsequent megaloblastic anemia . It affects people of all ages worldwide, particularly those over 60.

Detailed explanation-2: -There are a number of problems that can lead to a vitamin B12 or folate deficiency, including: pernicious anaemia – where your immune system attacks healthy cells in your stomach, preventing your body from absorbing vitamin B12 from the food you eat; this is the most common cause of vitamin B12 deficiency in the UK.

Detailed explanation-3: -This type of anemia is called “pernicious” because it was once considered a deadly disease. This was due to the lack of available treatment. Today, the condition is relatively easy to treat with vitamin B12 injections or possibly oral supplementation.