MCQ IN MEDICINE

MEDICINE MCQ

HAEMATOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Agglutination occurs when blood type antibodies come into contact with blood type antigens to which they correspond. What is agglutination?
A
Red blood cells burst and die
B
Red blood cells are clumped together and become non-functional
C
Antibodies bind to the antigens and then render the red blood cell non-functional
D
A system in which transfusions can occur
Explanation: 

Detailed explanation-1: -Agglutination is the process that occurs if an antigen is mixed with its corresponding antibody called isoagglutinin. This term is commonly used in blood grouping. This occurs in biology in two main examples: The clumping of cells such as bacteria or red blood cells in the presence of an antibody or complement.

Detailed explanation-2: -The blood will agglutinate if the antigens in the patient’s blood match the antibodies in the test tube. A antibodies attach to A antigens-they match like a lock and key-and thus form a clump of red blood cells. In the same way B antibodies attach to B antigens and Rh antibodies to Rh antigens.

Detailed explanation-3: -Individuals with type A blood-without any prior exposure to incompatible blood-have preformed antibodies to the B antigen circulating in their blood plasma. These antibodies, referred to as anti-B antibodies, will cause agglutination and hemolysis if they ever encounter erythrocytes with B antigens.

Detailed explanation-4: -Antibodies target and bind to specific antigens. For instance, anti-A antibodies target and bind to type A antigens. When the antibodies bind to these antigens, they clump red blood cells together. This clumping of cells is referred to as agglutination.

Detailed explanation-5: -Agglutination, which refers to the clumping of particles together, is an antigen-antibody reaction that occurs when an antigen (i.e., a molecule capable of triggering the adaptive immune response) is mixed with its corresponding antibody at a suitable pH and temperature.

There is 1 question to complete.