MCQ IN MEDICINE

MEDICINE MCQ

HAEMATOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cytotoxic T cells Attach to Which receptor prior to Initiating Apoptosis?
A
MHC Class 1
B
Viral Receptor
C
MHC Class 2
D
Nucleolar Receptor
Explanation: 

Detailed explanation-1: -Cytotoxic T cells recognize antigen bound to MHC protein type 1.

Detailed explanation-2: -Cytotoxic T cells (TC) express CD8, which recognizes class I MHC proteins, whereas helper T cells (TH) express CD4, which recognizes class II MHC proteins.

Detailed explanation-3: -1: MHC I are found on all nucleated body cells, and MHC II are found on macrophages, dendritic cells, and B cells (along with MHC I).

Detailed explanation-4: -The surface of a cytotoxic T-cell has something called a CD8 receptor. The CD8 receptor interacts with cells called major histocompatibility complex (MHC) Class I molecules to recognize when healthy cells are infected. When the CD8 receptor recognizes an infected cell, it activates the cytotoxic T-cells.

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