MCQ IN MEDICINE

MEDICINE MCQ

INFECTIOUS DISEASES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How did Dr. Edward Jenner prove that cowpox virus inoculation was efficient in protecting against smallpox virus infection?
A
He guessed.
B
He wrote a good article.
C
He infected himself.
D
He tested it and proved it.
Explanation: 

Detailed explanation-1: -To test his theory, Dr. Jenner took material from a cowpox sore on milkmaid Sarah Nelmes’ hand and inoculated it into the arm of James Phipps, the 9-year-old son of Jenner’s gardener. Months later, Jenner exposed Phipps several times to variola virus, but Phipps never developed smallpox.

Detailed explanation-2: -For many years, he had heard the tales that dairymaids were protected from smallpox naturally after having suffered from cowpox. Pondering this, Jenner concluded that cowpox not only protected against smallpox but also could be transmitted from one person to another as a deliberate mechanism of protection.

Detailed explanation-3: -After inoculation, vaccination using the cowpox virus became the primary defense against smallpox. After infection by the cowpox virus, the body (usually) gains the ability to recognize the similar smallpox virus from its antigens and is able to fight the smallpox disease much more efficiently.

Detailed explanation-4: -He used it in 1798 in the title of his Inquiry into the Variolae vaccinae known as the Cow Pox, in which he described the protective effect of cowpox against smallpox.

Detailed explanation-5: -The smallpox vaccine, introduced by Edward Jenner in 1796, was the first successful vaccine to be developed. He observed that milkmaids who previously had caught cowpox did not catch smallpox and showed that inoculated vaccinia protected against inoculated variola virus.

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