MCQ IN MEDICINE

MEDICINE MCQ

INFECTIOUS DISEASES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is a good example or analogy to use for host cells?
A
a human cell being attacked and intruded by influenza
B
the COVID-19 vaccine being administered to patients
C
an infected tick latching itself to and feeding off of a praying mantis
D
Febreze!
E
a wounded dog barking at a bird’s nest
Explanation: 

Detailed explanation-1: -The influenza virus’s hemagglutinin (HA) surface proteins then bind to the sialic acid receptors on the surface of a human respiratory tract cell. The structure of the influenza virus’s HA surface proteins is designed to fit the sialic acid receptors of the human cell, like a key to a lock.

Detailed explanation-2: -Influenza A virus (IAV) enters cells by binding to sialic acid on the cell surface. To accomplish this while avoiding immobilization by sialic acid in host mucus, viruses rely on a balance between the receptor-binding protein hemagglutinin (HA) and the receptor-cleaving protein neuraminidase (NA).

Detailed explanation-3: -The influenza viral spike that attaches to the cell receptor is the HA protein – hemagglutinin.

Detailed explanation-4: -T cells and B cells play key roles in adaptive immunity against the IAV infection. T cells are mainly known as CD4+ T and CD8+ T cells. CD8+ T cells differentiate into cytotoxic T lymphocytes (CTLs), which produce cytokines and effector molecules to restrict viral replication and kill virus-infected cells.

There is 1 question to complete.