MCQ IN MEDICINE

Detailed explanation-1: -Central nervous system (CNS) axons do not spontaneously regenerate after injury in adult mammals. In contrast, peripheral nervous system (PNS) axons readily regenerate, allowing recovery of function after peripheral nerve damage.

Detailed explanation-2: -When the spinal cord is injured, the damaged nerve fibers-called axons-are normally incapable of regrowth, leading to permanent loss of function. Considerable research has been done to find ways to promote the regeneration of axons following injury.

Detailed explanation-3: -Injured nerve cells in the central nervous system typically do not regenerate. However, this part of the nervous system can reorganize in response to an injury. This is called “plasticity.” Luckily, the brain has a lot of built-in redundancy.

Detailed explanation-4: -In humans, axons of the peripheral nervous system (PNS) are capable of regeneration, whereas those of the central nervous system (CNS) are currently viewed as incapable of regeneration. This inability of the CNS to regenerate poses significant issues for the treatment of injury and disease of the nervous system.

Detailed explanation-5: -Nerves can be easily damaged in a traumatic event, but can regenerate if the soma and a small portion of the neurilemma remain. Neuroregeneration refers to the regrowth or repair of nervous tissues, cells, or cell products. Such mechanisms may include generation of new neurons, glia, axons, myelin, or synapses.