MCQ IN MEDICINE

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MEDICINE MCQ

NEUROLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Semipermiable endothelial membrane, wich lines microvasculature of brain, separating blood from cerebrospinal fluid . Restricts the passage of pathogens ; diffusion of solutes in the blood, hydrophilic molecules into the cerebrospinal fluid while allowing the diffusion of hydrophobic molecules (O2, CO2, hormones) and small molecules
A
CSF
B
Arachnoid granullations
C
Blood brain bareer
D
none of them
Explanation: 

Detailed explanation-1: -The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that prevents solutes in the circulating blood from non-selectively crossing into the extracellular fluid of the central nervous system where neurons reside.

Detailed explanation-2: -The blood-brain barrier is the barrier between the cerebral capillary blood and the interstitial fluid of the brain. It is made up of capillary endothelial cells and basement membrane, neuroglial membrane, and glial podocytes, i.e., projections of astrocytes.

Detailed explanation-3: -Instead, the blood-CSF barrier at the choroid plexus is formed by the epithelial cells and the tight junctions that link them. The other part of the blood-CSF barrier is the arachnoid membrane, which envelops the brain. The cells of this membrane also are linked by tight junctions.

Detailed explanation-4: -The blood vessels that vascularize the central nervous system (CNS) possess unique properties, termed the blood–brain barrier, which allow these vessels to tightly regulate the movement of ions, molecules, and cells between the blood and the brain.

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