MEDICINE MCQ
RENAL MEDICINE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cell type of the glomerulus that stabilizes the glomerular architecture and is responsible for 40% of the hydraulic resistance of the filtration barrier.
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intercalated cells
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mesangial cells
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endothelial cells
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podocytes
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Explanation:
Detailed explanation-1: -The glomerular filtration barrier is composed of (1) pedicles of podocytes (visceral epithelium of Bowman’s capsule), (2) glomerular basement membrane (GBM) or basal lamina (produced by both endothelial and epithelial cells), and (3) the fenestrated endothelium of glomerular capillaries (Fig. 11-6).
Detailed explanation-2: -The kidney’s glomerular filtration barrier consists of two cells-podocytes and endothelial cells-and the glomerular basement membrane (GBM), a specialized extracellular matrix that lies between them.
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