MCQ IN MEDICINE

Detailed explanation-1: -The drug must be excreted rapidly from the body, so one strategy is to alter the urine pH to increase excretion. In aspirin poisoning for example, making the urine more alkaline with sodium bicarbonate increases ionisation of the salicylic acid (aspirin metabolite) therefore increasing its excretion from the body.

Detailed explanation-2: -Generally, a high BUN level means your kidneys aren’t working well. But elevated BUN can also be due to: Dehydration, resulting from not drinking enough fluids or for other reasons. Urinary tract obstruction. Congestive heart failure or recent heart attack.