MCQ IN MEDICINE

MEDICINE MCQ

RHEUMATOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the component of GABHS that is highly antigenic, and stimulates antibodies that cross-reacts with our body’s own cells (Molecular Mimicry)?
A
Streptokinase
B
Protein A
C
M Protein
D
Streptolysin
Explanation: 

Detailed explanation-1: -Molecular mimicry is the term used to describe immunological cross-reactivity between host and bacterial antigens. Immunological cross-reactions between streptococcal and host molecules have been identified by antibodies or T cells that react with streptococcal components and tissue antigens (6, 7, 22, 24, 25).

Detailed explanation-2: -Molecular or antigenic mimicry is a term for the similarity of different antigens, which can be confused by the immune system. Antigen recognition by antibodies and T cell receptors is specific, but not restricted to a single antigen.

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