PHYSIOLOGY
CARDIOVASCULAR PHYSIOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ADH
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EPO
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TSH
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GH
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Detailed explanation-1: -Erythropoietin (EPO) is the key hormone responsible for effective erythropoiesis, and iron is the essential mineral required for hemoglobin production. EPO allows survival and proliferation of erythroid precursor cells by generating intracellular signals resulting in the prevention of apoptosis.
Detailed explanation-2: -Erythropoietin (EPO) is a glycoprotein hormone, naturally produced by the peritubular cells of the kidney, that stimulates red blood cell production.
Detailed explanation-3: -Central to this mechanism is erythropoietin (EPO), a cytokine secreted by the kidney in response to low blood oxygen tension. Circulating EPO binds its cognate receptor (EPOR) on bone marrow erythroid progenitors, triggering multiple signaling pathways that support differentiation into mature RBCs.