MEDICAL PHYSIOLOGY

PHYSIOLOGY

CARDIOVASCULAR PHYSIOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The Blood Brain Barrier is a network of ____ with overlapping cell membranes that form ____ junctions.
A
Arterioles & Loose
B
Arterioles & Tight
C
Capillaries & Loose
D
Capillaries & Tight
Explanation: 

Detailed explanation-1: -The blood-brain barrier is the barrier between the cerebral capillary blood and the interstitial fluid of the brain. It is made up of capillary endothelial cells and basement membrane, neuroglial membrane, and glial podocytes, i.e., projections of astrocytes.

Detailed explanation-2: -The blood–brain barrier (BBB) is a highly complex and dynamic structure, mainly composed of brain microvascular endothelial cells (BMECs), pericytes, astrocytes and a non-cellular component-the basement membrane (BM).

Detailed explanation-3: -The blood–brain barrier is formed by endothelial cells of the capillary wall, astrocyte end-feet ensheathing the capillary, and pericytes embedded in the capillary basement membrane.

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