MEDICAL PHYSIOLOGY

Detailed explanation-1: -The Purkinje fibers (Czech: [ˈpurkɪɲɛ] ( listen); often incorrectly /pɜːrˈkɪndʒi/ pur-KIN-jee; Purkinje tissue or subendocardial branches) are located in the inner ventricular walls of the heart, just beneath the endocardium in a space called the subendocardium.

Detailed explanation-2: -Purkinje fibers play a major role in electrical conduction and propagation of impulse to the ventricular muscle. Many ventricular arrhythmias are initiated in the Purkinje fiber conduction system (eg.

Detailed explanation-3: -December 2017 was the 230th anniversary of Jan Evangelista Purkinje’s birth, which prompted us to review the life of this remarkable man who established the world’s first department of physiology in Wroclaw and whose name is immortalized in the cardiologic eponym, Purkinje fibers.