MEDICAL PHYSIOLOGY

PHYSIOLOGY

CENTRAL NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A 55-year old woman is diagnosed with Amyotrophic Lateral Sclerosis (ALS) and reports symptoms of general weakness, muscle atrophy, and muscle twitching. What type of nervous system dysfunction is she likely experiencing?
A
Upper motor neuron dysfunction
B
Lower motor neuron dysfunction
C
Axon degeneration
D
Demyelination
Explanation: 

Detailed explanation-1: -Muscle twitches in the arm, leg, shoulder, or tongue. Muscle cramps. Tight and stiff muscles (spasticity) Muscle weakness affecting an arm, a leg, the neck, or diaphragm.

Detailed explanation-2: -Amyotrophic lateral sclerosis (ALS) is a progressive disease characterized by motor neuron degeneration and skeletal muscle atrophy [1].

Detailed explanation-3: -Upper motor neuron disease causes stiffness, which is called “spasticity". Lower motor neuron disease causes weakness, loss of muscle ("atrophy") and muscle twitching ("fasciculations"). ALS may begin with abnormalities of upper or lower motor neurons.

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