MEDICAL PHYSIOLOGY

PHYSIOLOGY

CENTRAL NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Acetylcholine is synthesised and packaged in the presynaptic terminal before being released to act on the postsynaptic receptors. Which of these statements about that process in parasympathetic postganglionic neurons is not true?
A
Acetylcholine is synthesised by the action of choline-o-acetyltransferase on choline and acetyl coenzyme A.
B
Release of neurotransmitter is triggered when voltage sensitive calcium channels open to allow the influx of calcium
C
The released acetylcholine acts on postsynaptic nicotinic receptors
D
Choline is recycled by being taken back up into the presynaptic terminal
Explanation: 

Detailed explanation-1: -Answer and Explanation: The correct option is c. The acetylcholine that is released from the parasympathetic postganglionic neurons bind to the muscarinic receptors.

Detailed explanation-2: -ACh is removed from the synaptic cleft by acetylcholinesterase (AChE). The effects of ACh on the postsynaptic membrane are temporary. This is because the enzyme AChE (also called AChE or cholinesterase) is contained in the synaptic cleft and postsynaptic membrane.

Detailed explanation-3: -Acetylcholine is the chief neurotransmitter of the parasympathetic nervous system, the part of the autonomic nervous system (a branch of the peripheral nervous system) that contracts smooth muscles, dilates blood vessels, increases bodily secretions, and slows heart rate.

There is 1 question to complete.