MEDICAL PHYSIOLOGY

PHYSIOLOGY

CENTRAL NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Basal ganglia send direct projections to:-
A
primary motor area
B
premotor area
C
VA and VL thalamic nuclei
D
lower motor neurons in spinal cord
Explanation: 

Detailed explanation-1: -For the basal ganglia to work, nearly the entire cerebral cortex projects onto the striatum. The striatum then projects onto the thalamus, and from there neurons head back to the cerebral cortex through two pathways: the direct pathway-which is excitatory-and the indirect pathway, which is inhibitory.

Detailed explanation-2: -The direct pathway starts from the cortex and projects to the striatum (caudate nucleus and putamen) with excitatory glutamatergic (glu) neurons. The neurons from the striatum, which are inhibitory GABAergic, send their axons to the medial (internal) globus pallidus and substantia nigra, pars reticulata (SNr).

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